Back to top

Analyst Blog

The HealthCare segment of Bayer (BAYRY - Analyst Report) and partner, Onyx Pharmaceuticals Inc. recently announced positive results from the phase III DECISION study on Nexavar (sorafenib) tablets in patients suffering from locally advanced or metastatic radioactive iodine (RAI)-refractory differentiated thyroid cancer.

Bayer mentioned in its press release that currently there are no specific approved treatments for radioactive iodine refractory differentiated thyroid cancer.

Results from the study revealed a significant increase in progression-free survival (PFS) for patients treated with Nexavar compared to placebo. Data revealed a 41% reduction in the risk of disease progression or death for patients receiving Nexavar compared to patients under placebo. Bayer intends to present data from this study at the 49th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

Hand-foot skin reaction, diarrhea, alopecia, rash/desquamation, fatigue, weight loss and hypertension were some of the most common treatment-emergent adverse events in the Nexavar arm.

Bayer now plans to submit marketing authorization application for Nexavar for the treatment of RAI-refractory differentiated thyroid cancer based on the positive findings from the phase III DECISION study.

We note that Nexavar is already approved as an oral anti-cancer therapy for liver cancer and for the treatment of patients suffering from advanced kidney cancer in over 100 countries around the globe. The drug is also approved for the treatment of hepatocellular carcinoma and advanced renal cell carcinoma who have failed prior interferon-alpha/interleukin-2 based therapy or are considered unsuitable for such therapy in the EU.

Bayer presently carries a Zacks Rank #3 (Hold). Meanwhile, other stocks such as Jazz Pharmaceuticals (JAZZ - Analyst Report) and Santarus Inc. currently look more attractive carrying a Zacks Rank #1 (Strong Buy).

Please login to Zacks.com or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research

Close

Are you a new Zacks Member or a visitor to Zacks.com?

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Zacks.com. Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
CTPARTNERS… CTP 13.33 +3.49%
SAIA INC SAIA 45.65 +1.00%
VASCO DATA… VDSI 13.57 +0.67%
AMEDISYS IN… AMED 20.18 +0.10%
FIRSTSERVIC… FSRV 55.66 -0.13%