Back to top

Analyst Blog

Hyperion Therapeutics, Inc. (HPTX - Snapshot Report) recently acquired global rights to Buphenyl tablets and powder from Ucyclyd Pharma Inc., a subsidiary of Valeant Pharmaceuticals (VRX - Snapshot Report)

Buphenyl is approved by the US Food and Drug Administration (FDA) to treat urea cycle disorders (UCD).

As per the restated collaboration agreement with Ucyclyd, entered into in Mar 2012, Hyperion was given an option to purchase all of Ucyclyd’s worldwide rights to Buphenyl and Ammonul. A net amount of $11 million was paid to Hyperion; this reflects $32 million due to Hyperion on account of Ucyclyd retaining its rights to Ammonul, $19 million due to Ucyclyd for the purchase of rights to Buphenyl and a $2 million inventory adjustment due to Ucyclyd.

Last year, Hyperion had acquired worldwide rights to another drug, Ravicti, from Ucyclyd for an upfront payment of $6 million, future payments based upon the achievement of regulatory milestones in indications other than UCD, sales milestones, and mid-to-high single-digit royalties on global net sales of Ravicti.

Ravicti received FDA approval in Feb 2013 for the use as a nitrogen-binding agent for chronic management of adult and pediatric UCD patients more than two years of age who cannot be managed by dietary protein restriction and/or amino acid supplementation alone. Ravicti completed a phase II study for the treatment of hepatic encephalopathy (HE) in Apr 2012.

Hyperion currently carries a Zacks Rank #3 (Hold).Currently, companies like Santarus, Inc. and Jazz Pharmaceuticals (JAZZ - Analyst Report) look well positioned with a Zacks Rank #1 (Strong Buy).

Please login to Zacks.com or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research

Close

Are you a new Zacks Member or a visitor to Zacks.com?

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Zacks.com. Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
SYNAPTICS I… SYNA 78.11 +8.14%
CENTURY ALU… CENX 19.88 +5.74%
GREEN PLAIN… GPRE 39.41 +5.12%
PILGRIM'S P… PPC 28.82 +3.08%
THE PANTRY… PTRY 18.41 +2.79%