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Inovio (INO) Q4 Loss Wider than Expected; Shares Decline

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Inovio Pharmaceuticals, Inc.(INO - Free Report) reported a loss of 36 cents for the fourth quarter of 2016. The Zacks Consensus Estimate was of a loss of 29 cent per share. In the year-ago quarter, the company had posted loss of 25 cents.

Shares fell 5.4% in after-market trading. In fact, shares of Inovio have underperformed the Zacks classified Medical-Biomed/Genetics industry so far this year. The stock lost 1.0% during the period, while the industry registered a rise of 9.7%.

Quarter in Details

Inovio reported revenues of $8.5 million in the fourth quarter, which surpassed the Zacks Consensus Estimate of $6.6 million. Moreover, revenues grew 44% from the year-ago period.

Research and development expenses increased 53.2% to $23.9 million while general and administrative expenses increased 42.86% to $7.0 million.

Full-Year 2016 Results

Full-year 2016 loss per share was $1.01 per share, wider than the Zacks Consensus Estimate of a loss of 94 cents. In the year-ago period, the company had reported a loss of 43 cents.

Full-year 2016 revenues came in at $35.4 million, a decline of 12.81% from the year-ago period, primarily due to upfront payment of $15 million from MedImmune, the global biologics research and development arm of AstraZeneca PLC (AZN - Free Report) in 2015.

Pipeline Update

VGX-3100, an HPV immunotherapy, is the most advanced candidate in the company’s pipeline being developed for the treatment of HPV-16/18-related high-grade cervical dysplasia.

In Jan 2017, the company announced a collaboration and license agreement with China’s ApolloBio Corporation to exclusively develop and commercialize VGX-3100 in Greater China. Also, Inovio has submitted a regulatory package to the FDA for the initiation of phase III study on VGX-3100 for HPV-related high grade cervical dysplasia, which was placed on clinical hold in Oct 2016

In 2016, Roche Holding AG (RHHBY - Free Report) discontinued its collaboration for INO-1800, a hepatitis B DNA immunotherapy. This may have an impact on Inovio’s revenues as Roche was a significant customer in 2016. The enrolment of candidates has been completed for the phase I study, which is now being carried out independently by Inovio after Roche backed out.

The company expects to begin a phase I/II study for its immuno-oncology combination clinical study of INO-3112 and a new universal cancer vaccine, INO-5401 in the second half of 2017.

Inovio has started enrolment in a phase I study on vaccines being developed for Ebola, Zika and Middle East Respiratory Syndrome (MERS).

Inovio acquired Bioject Medical Technologies Inc., a pioneer in needle-free jet injection technology, in Mar 2017 for $5.5 million in cash and stock.

Inovio Pharmaceuticals, Inc. Price, Consensus and EPS Surprise

 

Inovio Pharmaceuticals, Inc. Price, Consensus and EPS Surprise | Inovio Pharmaceuticals, Inc. Quote

Zacks Rank & Key Picks

Inovio currently carries a Zacks Rank #2 (Buy). A better-ranked stock in the biomedical and genetics industry is Anthera Pharmaceuticals, Inc (ANTH - Free Report) . It sports a Zacks Rank #1 (Strong Buy). You can see the complete list of today’s Zacks #1 Rank stocks here.

Anthera’s loss of 36 cents was narrower than estimates of 41 cents for 2016. Anthera’s loss estimates narrowed from $1.49 to $1.17 for 2017 over the last 60 days.

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