Back to top

Analyst Blog

Endocyte Inc. (ECYT - Snapshot Report) recently announced that its oncology candidate, EC0652, achieved key objectives in a phase 0 study. Endocyte is developing the candidate as a treatment of patients suffering from prostate cancer.

EC0652 is a diagnostic imaging agent that targets prostate specific membrane antigen (PSMA), a protein expressed on cancer cells which originates from the prostate as well as on tumor neovasculature.

Endocyte also has plans to advance its corresponding therapeutic agent, EC1069. EC1069 is a proprietary PSMA-targeted small molecule drug conjugate (SMDC) linked with the anti-cancer drug tubulysin. Endocyte plans to file an Investigational New Drug (IND) application for EC1069 by the end of this year.

Meanwhile, the company’s focus remains on its oncology candidate, vintafolide (MK-8109/EC145). Last year, the company submitted a marketing authorization application (MAA) for the candidate in the EU. Endocyte is also looking for EU approval of an investigational companion diagnostic imaging agent etarfolatide (EC20) along with vintafolide. Both the candidates were granted orphan drug status in the EU.

Endocyte and its partner, Merck & Co. Inc. (MRK - Analyst Report), are looking to get vintafolide approved as a treatment of patients suffering from folate-receptor positive platinum-resistant ovarian cancer in combination with pegylated liposomal doxorubicin (PLD).

We remind investors that the oncology market is extremely competitive with the presence of companies like Roche Holding (RHHBY - Analyst Report).

We expect investor focus to remain on the European Medicine Agency’s decision regarding the approval of vintafolide and etarfolatide.

Endocyte carries a Zacks Rank #3 (Hold). However, Valeant Pharmaceuticals International Inc. (VRX - Analyst Report), currently looks more attractive in the pharma sector with a Zacks Rank #1 (Strong Buy).

Please login to or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research


Are you a new Zacks Member or a visitor to

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
ERBA DIAGNO… ERB 3.80 +7.04%
BANCO DO BR… BDORY 14.74 +5.66%
AIR INDUSTR… AIRI 9.99 +4.15%
EQT MIDSTRE… EQM 98.14 +3.38%
WEATHERFORD… WFT 23.64 +3.10%