Back to top

Analyst Blog

This page is temporarily not available.  Please check later as it should be available shortly. If you have any questions, please email customer support at or call 800-767-3771 ext.  9339.

Arena Pharmaceuticals, Inc. (ARNA - Snapshot Report) recently announced that patient dosing in a randomized, double-blind and placebo-controlled phase I study being conducted on APD334 has commenced.

The phase I study will focus on the safety, tolerability and pharmacokinetics of single-ascending doses of APD334. The candidate, which targets the sphingosine 1-phosphate subtype 1 (S1P1) receptor, may have the potential to be developed for autoimmune diseases like multiple sclerosis, psoriasis and rheumatoid arthritis.

While Arena Pharma is working on advancing its pipeline, we expect the company’s main focus to remain on the commercialization of its obesity drug, Belviq, in the US. Belviq gained Food and Drug Administration (FDA) approval in Jun 2012 for chronic weight management in adults who are overweight with a comorbidity or obese. Arena Pharma has an agreement with Eisai Inc. (ESALY) for the commercialization of Belviq in the US.

We expect investor focus to remain on the launch of Belviq in the US. The US Drug Enforcement Administration (DEA) issued a notice proposing that Belviq should be placed in Schedule IV of the Controlled Substances Act.

As far as the EU is concerned, Arena Pharma has responded to a Day 180 List of Outstanding Issues issued by the European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) earlier this year. The CHMP raised objections regarding non-clinical as well as clinical issues including tumors in rats, valvulopathy and psychiatric events. A response from the CHMP should be out in the first half of 2013.

Arena Pharma currently carries a Zacks Rank #3 (Hold). Companies that look more attractive include Cytokinetics Inc. (CYTK - Snapshot Report) and Osiris Therapeutics (OSIR - Analyst Report). Both are Zacks Rank #1 (Strong Buy) stocks.

Please login to or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research


Are you a new Zacks Member or a visitor to

Top Zacks Features

Learn more

Start for as little as $4.50 per trade.

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
VERTEX ENERG VTNR 8.28 +10.98%
MODINE MANUF MOD 17.20 +9.28%
CLAYTON WILL CWEI 139.99 +7.24%
E*TRADE FINA ETFC 22.66 +5.40%