We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies, revised Privacy Policy and Terms of Service.
You are being directed to ZacksTrade, a division of LBMZ Securities and licensed broker-dealer. ZacksTrade and Zacks.com are separate companies. The web link between the two companies is not a solicitation or offer to invest in a particular security or type of security. ZacksTrade does not endorse or adopt any particular investment strategy, any analyst opinion/rating/report or any approach to evaluating individual securities.
If you wish to go to ZacksTrade, click OK. If you do not, click Cancel.
CureVac (CVAC) Plummets on Disappointing COVID-19 Vaccine Data
Read MoreHide Full Article
Shares of Germany-based biopharmaceutical company, CureVac N.V. (CVAC - Free Report) , plunged 45.7% in the after-market trading hours after it announced disappointing data on its first-generation COVID-19 vaccine candidate, CVnCoV.
Results of the second interim analysis of its international phase IIb/III study in approximately 40,000 subjects (the HERALD study) showed that the candidate did not meet the prespecified statistical success criteria.
In this interim analysis, 134 COVID-19 cases were assessed. Out of these, 124 were sequenced to identify the variant causing the infection. The outcome confirms that only one single case was attributable to the original SARS-CoV-2 virus. More than half of the cases (57%) were caused by variants of concern. CVnCoV demonstrated an interim vaccine efficacy of only 47% against the COVID-19 disease of any severity.
The Data Safety Monitoring Board (DSMB) confirmed a favorable safety profile for CVnCoV. The study is continuing to the final analysis and the totality of the data will be assessed for the most appropriate regulatory pathway.
The HERALD study enrolled approximately 40,000 participants in ten countries in Latin America and Europe. The study is being conducted by CureVac in conjunction with Bayer (BAYRY - Free Report) . The second interim analysis included 134 cases, occurring at least two weeks after administration of the second dose.
The dismal results dampened hopes of a possible approval of the vaccine in the near term.
CureVac’s stock has gained 16.9% in the year so far against the industry’s decline of 0.7%.
Image Source: Zacks Investment Research
We note that the company began the development of mRNA-based COVID-19 vaccine candidates in January 2020. CVnCoV is an optimized, non-chemically modified mRNA, encoding the prefusion stabilized full-length spike protein of the SARS-CoV-2 virus.
In December 2020, CureVac initiated the HERALD study with a 12µg dose of CVnCoV. In February 2021, it initiated a rolling submission with the European Medicines Agency (EMA) for CVnCoV.
Last month, CureVac along with partner GlaxoSmithKline (GSK - Free Report) announced the first preclinical data in a rat model, which showed that its second-generation COVID-19 vaccine candidate, CV2CoV, induces high levels of antigen production as well as strong and dose-dependent immune responses in vaccinated animals.
There is a significant need for different vaccines across the globe to respond effectively to the emerging variants of COVID-19. Currently, players like Pfizer (PFE - Free Report) / BioNTech and Moderna are leading the vaccine race with their approved vaccines.
If you’re looking for big gains, there couldn’t be a better time to get in on a young industry primed to skyrocket from $17.7 billion back in 2019 to an expected $73.6 billion by 2027.
After a clean sweep of 6 election referendums in 5 states, pot is now legal in 36 states plus D.C. Federal legalization is expected soon and that could be a still greater bonanza for investors. Even before the latest wave of legalization, Zacks Investment Research has recommended pot stocks that have shot up as high as +285.9%
You’re invited to check out Zacks’ Marijuana Moneymakers: An Investor’s Guide. It features a timely Watch List of pot stocks and ETFs with exceptional growth potential.
Image: Bigstock
CureVac (CVAC) Plummets on Disappointing COVID-19 Vaccine Data
Shares of Germany-based biopharmaceutical company, CureVac N.V. (CVAC - Free Report) , plunged 45.7% in the after-market trading hours after it announced disappointing data on its first-generation COVID-19 vaccine candidate, CVnCoV.
Results of the second interim analysis of its international phase IIb/III study in approximately 40,000 subjects (the HERALD study) showed that the candidate did not meet the prespecified statistical success criteria.
In this interim analysis, 134 COVID-19 cases were assessed. Out of these, 124 were sequenced to identify the variant causing the infection. The outcome confirms that only one single case was attributable to the original SARS-CoV-2 virus. More than half of the cases (57%) were caused by variants of concern. CVnCoV demonstrated an interim vaccine efficacy of only 47% against the COVID-19 disease of any severity.
The Data Safety Monitoring Board (DSMB) confirmed a favorable safety profile for CVnCoV. The study is continuing to the final analysis and the totality of the data will be assessed for the most appropriate regulatory pathway.
The HERALD study enrolled approximately 40,000 participants in ten countries in Latin America and Europe. The study is being conducted by CureVac in conjunction with Bayer (BAYRY - Free Report) . The second interim analysis included 134 cases, occurring at least two weeks after administration of the second dose.
The dismal results dampened hopes of a possible approval of the vaccine in the near term.
CureVac’s stock has gained 16.9% in the year so far against the industry’s decline of 0.7%.
We note that the company began the development of mRNA-based COVID-19 vaccine candidates in January 2020. CVnCoV is an optimized, non-chemically modified mRNA, encoding the prefusion stabilized full-length spike protein of the SARS-CoV-2 virus.
In December 2020, CureVac initiated the HERALD study with a 12µg dose of CVnCoV. In February 2021, it initiated a rolling submission with the European Medicines Agency (EMA) for CVnCoV.
Last month, CureVac along with partner GlaxoSmithKline (GSK - Free Report) announced the first preclinical data in a rat model, which showed that its second-generation COVID-19 vaccine candidate, CV2CoV, induces high levels of antigen production as well as strong and dose-dependent immune responses in vaccinated animals.
There is a significant need for different vaccines across the globe to respond effectively to the emerging variants of COVID-19. Currently, players like Pfizer (PFE - Free Report) / BioNTech and Moderna are leading the vaccine race with their approved vaccines.
CureVac currently carries a Zacks Rank #3 (Hold). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
Time to Invest in Legal Marijuana
If you’re looking for big gains, there couldn’t be a better time to get in on a young industry primed to skyrocket from $17.7 billion back in 2019 to an expected $73.6 billion by 2027.
After a clean sweep of 6 election referendums in 5 states, pot is now legal in 36 states plus D.C. Federal legalization is expected soon and that could be a still greater bonanza for investors. Even before the latest wave of legalization, Zacks Investment Research has recommended pot stocks that have shot up as high as +285.9%
You’re invited to check out Zacks’ Marijuana Moneymakers: An Investor’s Guide. It features a timely Watch List of pot stocks and ETFs with exceptional growth potential.
Today, Download Marijuana Moneymakers FREE >>