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Isis Pharma Maintains a Buy

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We are reiterating or rating on Isis Pharmaceuticals ([url=]ISIS[/url]) of a Buy and maintaining our price target of $22.

We believe that antisense technology represents an exciting and potentially revolutionary platform for developing therapeutic candidates to treat a wide margin of diseases. In our view, antisense as a platform is today where biologics were 10 years ago.

The company's leading candidates are mipomersen (w/ Genzyme, [url=]GENZ[/url]) for high cholesterol and ISIS-113715 for diabetes, along with several other proprietary and partnered programs for oncology, inflammatory disease, asthma, and viral infections. Our financial model forecasts sustained profitability in 2011.

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