Pfizer and NCI Ink Research Deal Targeting Multiple Cancers

PFE MKGAF VNDA

Pfizer Inc. (PFE - Free Report) announced that it has struck a research and development agreement with the National Cancer Institute (NCI) to study three immunotherapy agents targeting multiple cancers.

The three immunotherapy agents include Pfizer’s proprietary immunotherapy agonistic monoclonal antibodies targeting OX40, utomilumab targeting 4-1BB, and avelumab an experimental anti-PD-L1 monoclonal antibody being developed in collaboration with Merck KGaA (MKGAF - Free Report) . These immuno-oncology assets will be studied alone as well as in various combinations.

The deal is in sync with Pfizer’s efforts to strengthen its immuno-oncology pipeline. The basic concept of immuno-oncology is to utilize certain parts of the immune system to fight the disease. This can be done by stimulating the immune system to attack cancer cells or by introducing immune system components into the body. While some immuno-oncology treatments have the potential to be effective as monotherapies, others may be more effective when combined with other treatments.

Pfizer enjoys a strong cancer franchise which currently consists of products like Ibrance, Xalkori and Sutent. The September acquisition of cancer-focused biopharma company Medivation added the latter’s prostate cancer treatment, Xtandi, to Pfizer’s portfolio. Cancer is the second-leading cause of death in the U.S. and a “Top 10” killer worldwide.

In a separate press release, Pfizer announced a tender offer to purchase for cash any and all of its outstanding 6.200% senior notes due March 15, 2019.

Zacks Rank & Stocks to Consider

Pfizer has a Zacks Rank #3 (Hold). Some better-ranked stocks in the health care sector include Vanda Pharmaceuticals, Inc. (VNDA - Free Report) and Cambrex Corporation . Both companies sport a Zacks Rank #1 (Strong Buy). You can see the complete list of today’s Zacks #1 Rank stocks here.

Vanda Pharma’s loss estimates have narrowed by 10% for 2016 while earnings estimates for 2017 have increased almost 30% over the last 30 days. The company posted a positive earnings surprise in three of the four trailing quarters, with an average beat of 56.65%. Its share price has increased 82% year to date.

Cambrex’s earnings estimates have increased almost 4% for 2016 and 5% for 2017 over the last 30 days. The company posted a positive earnings surprise in three of the four trailing quarters, with an average beat of 19.78%. Its share price has increased 13% year to date.

Zacks’ Best Private Investment Ideas

In addition to the recommendations that are available to the public on our website, how would you like to follow all Zacks' private buys and sells in real time?

Our experts cover all kinds of trades… from value to momentum . . . from stocks under $10 to ETF and option moves . . . from stocks that corporate insiders are buying up to companies that are about to report positive earnings surprises. You can even look inside exclusive portfolios that are normally closed to new investors. Starting today, for the next month, you can have unrestricted access. Click here for Zacks' private trades >>

Zacks Names "Single Best Pick to Double"

From thousands of stocks, 5 Zacks experts each have chosen their favorite to skyrocket +100% or more in months to come. From those 5, Director of Research Sheraz Mian hand-picks one to have the most explosive upside of all.

It’s a little-known chemical company that’s up 65% over last year, yet still dirt cheap. With unrelenting demand, soaring 2022 earnings estimates, and $1.5 billion for repurchasing shares, retail investors could jump in at any time.

This company could rival or surpass other recent Zacks’ Stocks Set to Double like Boston Beer Company which shot up +143.0% in little more than 9 months and NVIDIA which boomed +175.9% in one year.

Free: See Our Top Stock and 4 Runners Up >>