We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies, revised Privacy Policy and Terms of Service.
You are being directed to ZacksTrade, a division of LBMZ Securities and licensed broker-dealer. ZacksTrade and Zacks.com are separate companies. The web link between the two companies is not a solicitation or offer to invest in a particular security or type of security. ZacksTrade does not endorse or adopt any particular investment strategy, any analyst opinion/rating/report or any approach to evaluating individual securities.
If you wish to go to ZacksTrade, click OK. If you do not, click Cancel.
Prima Reports Favorable Initial Breast Cancer Study Data
Read MoreHide Full Article
Prima BioMed Ltd announced safety, pharmacokinetics and immuno-monitoring data from the first cohort of patients in a phase IIb chemo-immunotherapy study AIPAC (Active Immunotherapy PAClitaxel) on its most advanced pipeline candidate IMP321 (based on the LAG-3 immune control mechanism).
The multi-national, randomized, double-blind, placebo-controlled study on IMP321 in combination with Celgene Corp.’s Abraxane (paclitaxel) is currently ongoing for the treatment of hormone receptor-positive metastatic breast cancer.
Initial data demonstrated that 6 mg doses of IMP321 in combination with Abraxane was found to be safe and well tolerated with no drug-related serious adverse events. Moreover, data showed activation of blood monocytes/ dendritic cells and CD8 T cells.
Prima plans to start enrolling more patients in the second cohort, which will evaluate a 30 mg dose of IMP321. The company intends to present and compare data from both cohorts in the fourth quarter of 2016, following which it will enroll about 196 patients in the randomization phase with the recommended phase IIb dose.
IMP321 is also in a phase I combination therapy study (TACTI-mel) for the treatment of metastatic melanoma.
The company noted that many large pharmaceutical partners are developing LAG-3 products including antibodies for immune response modulation in autoimmunity and cancer.
Prima is a Zacks Rank #3 (Hold) stock. A couple of better-ranked stocks in the health care sector include ANI Pharmaceuticals, Inc. (ANIP - Free Report) and Retrophin, Inc. – both sporting a Zacks Rank #1 (Strong Buy).
Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report >>
See More Zacks Research for These Tickers
Pick one free report - opportunity may be withdrawn at any time
Image: Bigstock
Prima Reports Favorable Initial Breast Cancer Study Data
Prima BioMed Ltd announced safety, pharmacokinetics and immuno-monitoring data from the first cohort of patients in a phase IIb chemo-immunotherapy study AIPAC (Active Immunotherapy PAClitaxel) on its most advanced pipeline candidate IMP321 (based on the LAG-3 immune control mechanism).
The multi-national, randomized, double-blind, placebo-controlled study on IMP321 in combination with Celgene Corp.’s Abraxane (paclitaxel) is currently ongoing for the treatment of hormone receptor-positive metastatic breast cancer.
Initial data demonstrated that 6 mg doses of IMP321 in combination with Abraxane was found to be safe and well tolerated with no drug-related serious adverse events. Moreover, data showed activation of blood monocytes/ dendritic cells and CD8 T cells.
Prima plans to start enrolling more patients in the second cohort, which will evaluate a 30 mg dose of IMP321. The company intends to present and compare data from both cohorts in the fourth quarter of 2016, following which it will enroll about 196 patients in the randomization phase with the recommended phase IIb dose.
IMP321 is also in a phase I combination therapy study (TACTI-mel) for the treatment of metastatic melanoma.
The company noted that many large pharmaceutical partners are developing LAG-3 products including antibodies for immune response modulation in autoimmunity and cancer.
Prima is a Zacks Rank #3 (Hold) stock. A couple of better-ranked stocks in the health care sector include ANI Pharmaceuticals, Inc. (ANIP - Free Report) and Retrophin, Inc. – both sporting a Zacks Rank #1 (Strong Buy).
Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report >>