We use cookies to understand how you use our site and to improve your experience.
This includes personalizing content and advertising.
By pressing "Accept All" or closing out of this banner, you consent to the use of all cookies and similar technologies and the sharing of information they collect with third parties.
You can reject marketing cookies by pressing "Deny Optional," but we still use essential, performance, and functional cookies.
In addition, whether you "Accept All," Deny Optional," click the X or otherwise continue to use the site, you accept our Privacy Policy and Terms of Service, revised from time to time.
You are being directed to ZacksTrade, a division of LBMZ Securities and licensed broker-dealer. ZacksTrade and Zacks.com are separate companies. The web link between the two companies is not a solicitation or offer to invest in a particular security or type of security. ZacksTrade does not endorse or adopt any particular investment strategy, any analyst opinion/rating/report or any approach to evaluating individual securities.
If you wish to go to ZacksTrade, click OK. If you do not, click Cancel.
PDS Biotech (PDSB) Completes Enrollment for HPV Cancer Study
Read MoreHide Full Article
PDS Biotech (PDSB - Free Report) stock rose almost 5% as the company completed enrollment in the immune checkpoint inhibitor naïve group of its VERSATILE-002 phase II study on pipeline candidate PDS0101 for treating adults with HPV16-positive unresectable recurrent or metastatic head and neck squamous cell carcinoma (“HNSCC”).
The mid-stage study, VERSATILE-002, is an open-label study being conducted across multiple centers. The study aims to evaluate the efficacy and safety of its lead candidate PDS0101, which is administered in combination with Keytruda (pembrolizumab). Keytruda is Merck’s (MRK - Free Report) anti-PD-1 therapy that helps immune cells kill cancer cells in different cancer indications.
The study aims to examine two patient groups. The first group comprises those who have not previously received an immune checkpoint inhibitor (ICI), referred to as the ICI naïve cohort. The second group includes those who have failed prior treatments, including ICI therapy, referred to as ICI refractory group.
Shares of PDS Biotech have fallen 44% year to date compared with the industry’s 7.8% decline.
Image Source: Zacks Investment Research
In December 2022, the company completed enrollment in the ICI refractory group. PDS0101, in combination with Keytruda, has been granted Fast Track designation in June 2022. The Fast Track designation is designed to expedite the review of drug candidates that could potentially treat serious or life-threatening conditions.
The company plans to initiate phase III study (VERSATILE-003) by the end of this year.
PDS0101 is also being evaluated in triple combination with M9241 (now PDS0301) and bintrafusp alfa for HPV-16 patients with HNSCC. The study is being led by National Cancer Institute.
The company is advancing its development candidates PDS0102, PDS0103 and PDS0104, targeting different cancer indications.
In the past 60 days, the Zacks Consensus Estimate for Allogene Therapeutics’ 2023 and 2024 loss per share has narrowed from $2.50 to $2.32 and $2.48 to $2.21, respectively. Shares of ALLO have declined 3.4% in the year-to-date period.
Allogene’s earnings beat estimates in three of the last four quarters and missed the mark on one occasion, the average surprise being 5.08%.
In the past 60 days, the Zacks Consensus Estimate for Halozyme Therapeutics’ 2024 earnings have increased from $3.75 per share to $3.76. Shares of HALO have plunged 41.5% in the year-to-date period.
Halozyme Therapeutics’ earnings beat estimates in three of the last four quarters and missed the mark once, the average surprise being 12.09%.
See More Zacks Research for These Tickers
Normally $25 each - click below to receive one report FREE:
Image: Bigstock
PDS Biotech (PDSB) Completes Enrollment for HPV Cancer Study
PDS Biotech (PDSB - Free Report) stock rose almost 5% as the company completed enrollment in the immune checkpoint inhibitor naïve group of its VERSATILE-002 phase II study on pipeline candidate PDS0101 for treating adults with HPV16-positive unresectable recurrent or metastatic head and neck squamous cell carcinoma (“HNSCC”).
The mid-stage study, VERSATILE-002, is an open-label study being conducted across multiple centers. The study aims to evaluate the efficacy and safety of its lead candidate PDS0101, which is administered in combination with Keytruda (pembrolizumab). Keytruda is Merck’s (MRK - Free Report) anti-PD-1 therapy that helps immune cells kill cancer cells in different cancer indications.
The study aims to examine two patient groups. The first group comprises those who have not previously received an immune checkpoint inhibitor (ICI), referred to as the ICI naïve cohort. The second group includes those who have failed prior treatments, including ICI therapy, referred to as ICI refractory group.
Shares of PDS Biotech have fallen 44% year to date compared with the industry’s 7.8% decline.
Image Source: Zacks Investment Research
In December 2022, the company completed enrollment in the ICI refractory group. PDS0101, in combination with Keytruda, has been granted Fast Track designation in June 2022. The Fast Track designation is designed to expedite the review of drug candidates that could potentially treat serious or life-threatening conditions.
The company plans to initiate phase III study (VERSATILE-003) by the end of this year.
PDS0101 is also being evaluated in triple combination with M9241 (now PDS0301) and bintrafusp alfa for HPV-16 patients with HNSCC. The study is being led by National Cancer Institute.
The company is advancing its development candidates PDS0102, PDS0103 and PDS0104, targeting different cancer indications.
PDS Biotechnology Corporation Price and Consensus
PDS Biotechnology Corporation price-consensus-chart | PDS Biotechnology Corporation Quote
Zacks Rank and Stocks to Consider
Currently, PDS Biotech carries a Zacks Rank #3 (Hold).
A couple of better-ranked stocks in the same sector are Allogene Therapeutics (ALLO - Free Report) and Halozyme Therapeutics (HALO - Free Report) , both carrying a Zacks Rank #2 (Buy) at present. You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.
In the past 60 days, the Zacks Consensus Estimate for Allogene Therapeutics’ 2023 and 2024 loss per share has narrowed from $2.50 to $2.32 and $2.48 to $2.21, respectively. Shares of ALLO have declined 3.4% in the year-to-date period.
Allogene’s earnings beat estimates in three of the last four quarters and missed the mark on one occasion, the average surprise being 5.08%.
In the past 60 days, the Zacks Consensus Estimate for Halozyme Therapeutics’ 2024 earnings have increased from $3.75 per share to $3.76. Shares of HALO have plunged 41.5% in the year-to-date period.
Halozyme Therapeutics’ earnings beat estimates in three of the last four quarters and missed the mark once, the average surprise being 12.09%.