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Compared to Estimates, Pfizer (PFE) Q1 Earnings: A Look at Key Metrics

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For the quarter ended March 2025, Pfizer (PFE - Free Report) reported revenue of $13.72 billion, down 7.8% over the same period last year. EPS came in at $0.92, compared to $0.82 in the year-ago quarter.

The reported revenue represents a surprise of -0.88% over the Zacks Consensus Estimate of $13.84 billion. With the consensus EPS estimate being $0.64, the EPS surprise was +43.75%.

While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Pfizer performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:

  • Revenues- Oncology- Ibrance- United States: $659 million versus the three-analyst average estimate of $565.50 million. The reported number represents a year-over-year change of -3%.
  • Revenues- Primary Care- Eliquis alliance revenues and direct sales- United States: $1.30 billion versus $1.39 billion estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -8.1% change.
  • Revenues- Specialty Care- Enbrel- Total International: $140 million versus the three-analyst average estimate of $132.28 million. The reported number represents a year-over-year change of -12%.
  • Revenues- Oncology- Ibrance- Total International: $318 million versus $333.47 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -15.2% change.
  • Revenues- Oncology- Ibrance- Worldwide: $977 million versus $898.97 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -7.3% change.
  • Revenue- Specialty Care- Cibinqo: $58 million versus $71.20 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a +38.1% change.
  • Revenues- Specialty Care- Xeljanz- Worldwide: $128 million compared to the $141.92 million average estimate based on three analysts. The reported number represents a change of -34% year over year.
  • Revenues- Oncology- Inlyta- Worldwide: $219 million compared to the $207.30 million average estimate based on three analysts. The reported number represents a change of -7.6% year over year.
  • Revenue- Specialty Care- Worldwide: $3.99 billion versus the three-analyst average estimate of $3.98 billion. The reported number represents a year-over-year change of +3.8%.
  • Revenue- Primary Care- Worldwide: $5.70 billion versus $5.82 billion estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -21% change.
  • Revenues- Oncology- Xtandi alliance revenues- United States: $458 million versus $419.37 million estimated by three analysts on average.
  • Revenues- Oncology- Xtandi alliance revenues- Worldwide: $458 million compared to the $419.37 million average estimate based on three analysts.
View all Key Company Metrics for Pfizer here>>>

Shares of Pfizer have returned -9% over the past month versus the Zacks S&P 500 composite's -0.8% change. The stock currently has a Zacks Rank #2 (Buy), indicating that it could outperform the broader market in the near term.

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