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Compared to Estimates, Illumina (ILMN) Q2 Earnings: A Look at Key Metrics

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For the quarter ended June 2025, Illumina (ILMN - Free Report) reported revenue of $1.06 billion, down 4.8% over the same period last year. EPS came in at $1.19, compared to $0.36 in the year-ago quarter.

The reported revenue compares to the Zacks Consensus Estimate of $1.05 billion, representing a surprise of +1.11%. The company delivered an EPS surprise of +16.67%, with the consensus EPS estimate being $1.02.

While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their next move, some key metrics always offer a more accurate picture of a company's financial health.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Illumina performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
  • Revenue- Core Illumina- Instruments: $101 million compared to the $94.4 million average estimate based on three analysts. The reported number represents a change of -15.8% year over year.
  • Revenue- Product revenue- Consumable: $811 million versus $788.41 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -0.5% change.
  • Revenue- Service and other revenue: $147 million versus $157.99 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -20.5% change.
  • Revenue- Product revenue: $912 million compared to the $888.52 million average estimate based on three analysts. The reported number represents a change of -1.6% year over year.
  • Revenue- Core Illumina- Service and other revenue: $147 million versus the three-analyst average estimate of $159.52 million. The reported number represents a year-over-year change of -6.4%.
  • Revenue- Core Illumina- Consumables: $811 million versus $792.14 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -0.5% change.
  • Revenue- Product revenue- Instruments: $101 million compared to the $115.79 million average estimate based on three analysts. The reported number represents a change of -15.8% year over year.
  • Revenue- Core Illumina- Total product revenue: $912 million versus $886.54 million estimated by three analysts on average. Compared to the year-ago quarter, this number represents a -2.5% change.
  • Revenue- Sequencing- Instruments: $96 million versus the two-analyst average estimate of $111.69 million. The reported number represents a year-over-year change of -17.2%.
  • Revenue- Sequencing- Consumables: $740 million versus the two-analyst average estimate of $705.59 million. The reported number represents a year-over-year change of +0.4%.
  • Revenue- Microarrays- Instruments: $5 million versus $3.45 million estimated by two analysts on average. Compared to the year-ago quarter, this number represents a +25% change.
  • Revenue- Microarrays- Consumables: $71 million compared to the $79.28 million average estimate based on two analysts. The reported number represents a change of -9% year over year.

View all Key Company Metrics for Illumina here>>>

Shares of Illumina have returned +6.3% over the past month versus the Zacks S&P 500 composite's +2.7% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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