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Lilly (LLY) Reports Q2 Earnings: What Key Metrics Have to Say

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Eli Lilly (LLY - Free Report) reported $15.56 billion in revenue for the quarter ended June 2025, representing a year-over-year increase of 37.6%. EPS of $6.31 for the same period compares to $3.92 a year ago.

The reported revenue compares to the Zacks Consensus Estimate of $14.75 billion, representing a surprise of +5.48%. The company delivered an EPS surprise of +12.48%, with the consensus EPS estimate being $5.61.

While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Lilly performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
  • Net Sales- US-Alimta [$M]: $7.9 million versus $8.04 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a -36.8% change.
  • Net Sales- International-Humulin [$M]: $53 million compared to the $51.12 million average estimate based on four analysts. The reported number represents a change of -2.2% year over year.
  • Net Sales- Cyramza (Ramucirumab /IMC-1121B) - ROW: $131.9 million versus $130.32 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a -0.7% change.
  • Net Sales- Cyramza (Ramucirumab /IMC-1121B) - US: $121.8 million versus the four-analyst average estimate of $115.88 million. The reported number represents a year-over-year change of +4.9%.
  • Net Sales- Cyramza (Ramucirumab /IMC-1121B)- Total: $253.7 million versus the four-analyst average estimate of $246.2 million. The reported number represents a year-over-year change of +1.9%.
  • Net Sales- Humulin [$M]: $175.2 million versus $206.1 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a -21.7% change.
  • Net Sales- Humalog [$M]: $503.1 million versus $609.52 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a -20.4% change.
  • Net Sales- Forteo [$M]: $92.5 million versus $62.76 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a +32.3% change.
  • Net Sales- Erbitux [$M]: $183.7 million versus $156.28 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a +17.9% change.
  • Net Sales- Alimta [$M]: $28.9 million versus the four-analyst average estimate of $25.08 million. The reported number represents a year-over-year change of -14.8%.
  • Net Sales- Oncology [$M]: $2.41 billion compared to the $2.43 billion average estimate based on four analysts. The reported number represents a change of +11.8% year over year.
  • Net Sales- Neurosciences: $344 million versus $336.92 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a +1.3% change.

View all Key Company Metrics for Lilly here>>>

Shares of Lilly have returned -5.2% over the past month versus the Zacks S&P 500 composite's +1.2% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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