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TEVA Signs Deal With RPRX to Accelerate Development of Vitiligo Drug
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Key Takeaways
Teva signed a deal with RPRX for the speedy development of anti-IL-15 antibody TEV-'408 for vitiligo.
RPRX will co-fund a phase IIb vitiligo study, with an option to invest in phase III pending results.
TEVA keeps rights while paying milestones and royalties if approved, lowering risk via non-dilutive funding.
Teva Pharmaceuticals (TEVA - Free Report) announced a funding agreement with Royalty Pharma plc (RPRX - Free Report) , under which the latter will provide up to $500 million to accelerate the development of Teva’s anti-IL-15 antibody, TEV-’408. IL-15 plays a central role in driving multiple immune-mediated disease pathways. The candidate is currently in early-stage development for vitiligo and other autoimmune diseases.
Royalty Pharma’s $500 million commitment includes $75 million in R&D co-funding for a phase IIb vitiligo study expected to begin in 2026, with an option to invest a further $425 million to co-fund phase III development pending phase IIb results. If the drug is eventually approved and commercialized, Teva will pay Royalty Pharma a milestone payment and ongoing royalties on global net sales.
How Does the Deal Benefit TEVA?
Teva has strengthened its immunology pipeline through a strategic collaboration with Royalty Pharma, which significantly de-risks and accelerates the development of TEV-’408 for vitiligo. The partnership provides substantial non-dilutive funding to Teva, enabling faster clinical progression and positioning the company to move more efficiently through mid- and late-stage development.
The structure of the $500 million funding agreement with Royalty Pharma reduces Teva’s financial exposure while preserving meaningful long-term upside through full commercial control, milestone achievements, and global sales.
In the past six months, Teva’s shares have rallied 95% compared with the industry’s 54.1% growth.
Image Source: Zacks Investment Research
Per TEVA, early phase Ib data from the ongoing TEV-’408 vitiligo study offer initial validation of IL-15 as a promising therapeutic target across a wide range of autoimmune diseases. Additional clinical updates from the vitiligo program are expected in 2026.
Vitiligo is a chronic autoimmune condition marked by loss of skin pigmentation. It represents a large and underpenetrated market with limited treatment options and no approved systemic therapies. With a global prevalence estimated at 0.5% to 2% and a significant unmet medical need, TEV-’408 could address both the physical and psychosocial burden of the disease by targeting the IL-15 pathway responsible for immune-driven melanocyte destruction.
Please note that TEVA is also currently evaluating TEV-’408 in a phase IIa study for celiac disease. In 2025, the FDA granted the Fast Track designation to the candidate for the celiac disease indication, underscoring its potential clinical and regulatory value.
TEVA’s Ongoing Collaboration Deal With RPRX
The funding agreement for TEV-’408 clinical development marks Teva’s second collaboration agreement with Royalty Pharma.
The companies first entered into a funding agreement in 2023 to accelerate the development of Teva’s long-acting injectable olanzapine (TEV-’749) for schizophrenia. Royalty Pharma committed up to $100 million to cover development costs, which Teva has already fully received and recognized as R&D reimbursement.
Per the agreement, Teva retained global development and commercialization rights of the candidate, but is liable to make milestone and royalty payments to RPRX upon its potential approval and launch. Last month, TEVA announced submitting a new drug application to the FDA seeking approval for olanzapine to treat adults with schizophrenia.
Teva Pharmaceutical Industries Ltd. Price and Consensus
Over the past 60 days, 2026 EPS estimates for CorMedix have risen from $2.49 to $2.88. Shares of CRMD have lost 32.8% over the past six months.
CorMedix’s earnings beat estimates in each of the trailing four quarters, with the average surprise being 27.04%.
Over the past 60 days, estimates for Indivior’s earnings per share for 2026 have risen to $2.85 from $2.60. Indivior stock has rallied 126.9% over the past six months.
Indivior’s earnings beat estimates in three of the trailing four quarters and were in line in the remaining quarter, with the average surprise being 68%.
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TEVA Signs Deal With RPRX to Accelerate Development of Vitiligo Drug
Key Takeaways
Teva Pharmaceuticals (TEVA - Free Report) announced a funding agreement with Royalty Pharma plc (RPRX - Free Report) , under which the latter will provide up to $500 million to accelerate the development of Teva’s anti-IL-15 antibody, TEV-’408. IL-15 plays a central role in driving multiple immune-mediated disease pathways. The candidate is currently in early-stage development for vitiligo and other autoimmune diseases.
Royalty Pharma’s $500 million commitment includes $75 million in R&D co-funding for a phase IIb vitiligo study expected to begin in 2026, with an option to invest a further $425 million to co-fund phase III development pending phase IIb results. If the drug is eventually approved and commercialized, Teva will pay Royalty Pharma a milestone payment and ongoing royalties on global net sales.
How Does the Deal Benefit TEVA?
Teva has strengthened its immunology pipeline through a strategic collaboration with Royalty Pharma, which significantly de-risks and accelerates the development of TEV-’408 for vitiligo. The partnership provides substantial non-dilutive funding to Teva, enabling faster clinical progression and positioning the company to move more efficiently through mid- and late-stage development.
The structure of the $500 million funding agreement with Royalty Pharma reduces Teva’s financial exposure while preserving meaningful long-term upside through full commercial control, milestone achievements, and global sales.
In the past six months, Teva’s shares have rallied 95% compared with the industry’s 54.1% growth.
Image Source: Zacks Investment Research
Per TEVA, early phase Ib data from the ongoing TEV-’408 vitiligo study offer initial validation of IL-15 as a promising therapeutic target across a wide range of autoimmune diseases. Additional clinical updates from the vitiligo program are expected in 2026.
Vitiligo is a chronic autoimmune condition marked by loss of skin pigmentation. It represents a large and underpenetrated market with limited treatment options and no approved systemic therapies. With a global prevalence estimated at 0.5% to 2% and a significant unmet medical need, TEV-’408 could address both the physical and psychosocial burden of the disease by targeting the IL-15 pathway responsible for immune-driven melanocyte destruction.
Please note that TEVA is also currently evaluating TEV-’408 in a phase IIa study for celiac disease. In 2025, the FDA granted the Fast Track designation to the candidate for the celiac disease indication, underscoring its potential clinical and regulatory value.
TEVA’s Ongoing Collaboration Deal With RPRX
The funding agreement for TEV-’408 clinical development marks Teva’s second collaboration agreement with Royalty Pharma.
The companies first entered into a funding agreement in 2023 to accelerate the development of Teva’s long-acting injectable olanzapine (TEV-’749) for schizophrenia. Royalty Pharma committed up to $100 million to cover development costs, which Teva has already fully received and recognized as R&D reimbursement.
Per the agreement, Teva retained global development and commercialization rights of the candidate, but is liable to make milestone and royalty payments to RPRX upon its potential approval and launch. Last month, TEVA announced submitting a new drug application to the FDA seeking approval for olanzapine to treat adults with schizophrenia.
Teva Pharmaceutical Industries Ltd. Price and Consensus
Teva Pharmaceutical Industries Ltd. price-consensus-chart | Teva Pharmaceutical Industries Ltd. Quote
TEVA's Zacks Rank & Stocks to Consider
Teva currently carries a Zacks Rank #3 (Hold).
Some better-ranked stocks in the biotech sector are CorMedix (CRMD - Free Report) and Indivior (INDV - Free Report) , each currently sporting a Zacks Rank #1 (Strong Buy). You can see the complete list of today’s Zacks #1 Rank stocks here.
Over the past 60 days, 2026 EPS estimates for CorMedix have risen from $2.49 to $2.88. Shares of CRMD have lost 32.8% over the past six months.
CorMedix’s earnings beat estimates in each of the trailing four quarters, with the average surprise being 27.04%.
Over the past 60 days, estimates for Indivior’s earnings per share for 2026 have risen to $2.85 from $2.60. Indivior stock has rallied 126.9% over the past six months.
Indivior’s earnings beat estimates in three of the trailing four quarters and were in line in the remaining quarter, with the average surprise being 68%.