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PCRX, LG Chem Partner to Expand Exparel Reach Across the Asia-Pacific

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Key Takeaways

  • PCRX partnered with LG Chem, granting exclusive rights to sell Exparel in select Asia-Pacific markets.
  • PCRX will manufacture Exparel as LG Chem leads regulatory filings starting with South Korea and Thailand.
  • PCRX will receive upfront payment, transfer pricing and tiered royalties as it seeks new revenue streams.

Pacira BioSciences (PCRX - Free Report) announced a partnership with LG Chem to broaden access to opioid-sparing postsurgical pain management across select Asia-Pacific markets. Under the agreement, LG Chem receives exclusive rights to commercialize Exparel (bupivacaine liposome injectable suspension), Pacira’s long-acting local anesthetic for postsurgical pain control in the region.

In consideration for the transaction, Pacira BioSciences will receive an undisclosed upfront payment, a transfer price, and tiered royalties on future sales generated by LG Chem in the licensed markets. PCRX will manufacture Exparel, while LG Chem will handle regulatory filings and approvals in the region, with plans to submit marketing authorization applications in South Korea and Thailand within the next six months.

The Rationale Behind PCRX’s Exparel Deal

Pacira BioSciences’ agreement with LG Chem is designed to extend Exparel’s reach into select Asia-Pacific markets while supporting the company’s long-term growth strategy. The partnership enables PCRX to tap into a large surgical patient base in the region and broaden the availability of its pain therapy beyond its core geographies.

The collaboration is underpinned by a clear clinical and commercial opportunity. In many Asian markets, postsurgical pain management continues to rely on short-acting analgesics with limited durability and variable effectiveness, creating demand for more advanced solutions that can support faster recovery and improved patient outcomes. Exparel’s extended duration of action positions it as a differentiated option for hospitals and surgeons seeking better perioperative pain control.

In the past six months, PCRX shares have lost 5% against the industry’s 22.9% growth.

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The deal allows Pacira BioSciences to scale internationally through an established regional partner with deep expertise in orthopedic and surgical care, rather than building a standalone commercial infrastructure. Leveraging LG Chem’s market access and regulatory capabilities is likely to accelerate adoption, while providing Pacira BioSciences with upfront and recurring revenue streams through transfer pricing and royalties.

Importantly for investors, the partnership is expected to expand Exparel’s commercial footprint and open new revenue channels outside the United States. This comes at a time when Pacira BioSciences reported preliminary fourth-quarter revenues of $196.9 million, up 5% year over year, but below market expectations, which triggered a decline in the share price last week. Management is positioning the international expansion of Exparel as a key lever to drive incremental sales and improve overall revenue momentum.

PCRX’s Other Marketed Products

Apart from Exparel, Pacira BioSciences’ marketed portfolio of products comprises two other products — Zilretta and the iovera system.

Zilretta is approved as an extended-release intra-articular therapy providing relief to osteoarthritis patients with knee pain. The iovera system, on the other hand, is a hand-held medical device used to deliver a precise, controlled application of cold temperature to targeted nerves.

PCRX’s Zacks Rank & Stocks to Consider

Pacira BioSciences currently carries a Zacks Rank #3 (Hold).

Some better-ranked stocks in the biotech sector are Amicus Therapeutics (FOLD - Free Report) , Alkermes (ALKS - Free Report) , and Krystal Biotech (KRYS - Free Report) , each sporting a Zacks Rank #1 (Strong Buy) at present. You can see the complete list of today’s Zacks #1 Rank stocks here.

Over the past 60 days, estimates for Amicus Therapeutics’ 2026 EPS have decreased from 67 cents to 65 cents. Shares of FOLD have surged 142.1% over the past six months.

Amicus Therapeutics’ earnings beat estimates in one of the trailing four quarters, missing the mark on the other three occasions, delivering an average negative surprise of 20.21%.

Over the past 60 days, 2026 EPS estimates for Alkermes have remained constant at $1.54. Shares of ALKS have lost 37.7% over the past six months.

Alkermes’ earnings beat estimates in three of the trailing four quarters, missing on the remaining occasion, with the average surprise being 4.58%.

Over the past 60 days, estimates for Krystal Biotech’s EPS for 2026 have risen to $8.46 from $8.34. KRYS stock has rallied 120.9% over the past six months.

Krystal Biotech’s earnings beat estimates in three of the trailing four quarters and missed in the remaining quarter, with the average surprise being 40.43%.

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