For the quarter ended December 2025, Natera (NTRA Quick QuoteNTRA - Free Report) reported revenue of $665.5 million, up 39.8% over the same period last year. EPS came in at $0.35, compared to -$0.41 in the year-ago quarter.

The reported revenue compares to the Zacks Consensus Estimate of $660.45 million, representing a surprise of +0.76%. The company delivered an EPS surprise of +175.43%, with the consensus EPS estimate being -$0.46.

While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.

Since these metrics play a crucial role in driving the top- and bottom-line numbers, comparing them with the year-ago numbers and what analysts estimated about them helps investors better project a stock's price performance.

Here is how Natera performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:

• Volume - Tests processed: 923,600 versus the three-analyst average estimate of 903,207.
• Revenues- Licensing and other: $4.34 million versus $2.32 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a +37.7% change.
• Revenues- Product: $661.16 million versus $570.94 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a +39.8% change.

View all Key Company Metrics for Natera here>>>

Shares of Natera have returned -10.2% over the past month versus the Zacks S&P 500 composite's +0.6% change. The stock currently has a Zacks Rank #4 (Sell), indicating that it could underperform the broader market in the near term.