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Compared to Estimates, Ionis Pharmaceuticals (IONS) Q1 Earnings: A Look at Key Metrics
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Ionis Pharmaceuticals (IONS - Free Report) reported $246 million in revenue for the quarter ended March 2026, representing a year-over-year increase of 86.4%. EPS of -$0.30 for the same period compares to -$0.75 a year ago.
The reported revenue compares to the Zacks Consensus Estimate of $190.41 million, representing a surprise of +29.2%. The company delivered an EPS surprise of +64.71%, with the consensus EPS estimate being -$0.85.
While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their next move, some key metrics always offer a more accurate picture of a company's financial health.
As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.
Here is how Ionis Pharmaceuticals performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
Revenue- Total research and development revenue: $138 million compared to the $66.63 million average estimate based on eight analysts. The reported number represents a change of +146.4% year over year.
Revenue- Total commercial revenue: $108 million versus the eight-analyst average estimate of $123.78 million. The reported number represents a year-over-year change of +42.1%.
Royalty revenue- SPINRAZA royalties: $44 million compared to the $48.81 million average estimate based on seven analysts.
Product sales, net: $43 million compared to the $45.43 million average estimate based on seven analysts.
Royalty revenue- WAINUA royalties: $11 million versus $16.13 million estimated by seven analysts on average.
Product sales net- TRYNGOLZA sales: $27 million versus $34.02 million estimated by seven analysts on average.
Product sales net- DAWNZERA sales: $16 million versus the seven-analyst average estimate of $11.41 million.
Revenue- Commercial revenue- Other commercial revenue: $7 million versus the six-analyst average estimate of $6.8 million. The reported number represents a year-over-year change of +16.7%.
Royalty revenue: $58 million compared to the $71.07 million average estimate based on six analysts.
Royalty revenue- Other royalties: $3 million versus $6.16 million estimated by six analysts on average.
Revenue- Research and development revenue- WAINUA joint development revenue: $18 million versus $9.03 million estimated by five analysts on average. Compared to the year-ago quarter, this number represents a +80% change.
Revenue- Research and development revenue- Collaborative agreement revenue: $120 million versus $52.27 million estimated by five analysts on average. Compared to the year-ago quarter, this number represents a +160.9% change.
Shares of Ionis Pharmaceuticals have returned -4.4% over the past month versus the Zacks S&P 500 composite's +12.2% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.
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Compared to Estimates, Ionis Pharmaceuticals (IONS) Q1 Earnings: A Look at Key Metrics
Ionis Pharmaceuticals (IONS - Free Report) reported $246 million in revenue for the quarter ended March 2026, representing a year-over-year increase of 86.4%. EPS of -$0.30 for the same period compares to -$0.75 a year ago.
The reported revenue compares to the Zacks Consensus Estimate of $190.41 million, representing a surprise of +29.2%. The company delivered an EPS surprise of +64.71%, with the consensus EPS estimate being -$0.85.
While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their next move, some key metrics always offer a more accurate picture of a company's financial health.
As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.
Here is how Ionis Pharmaceuticals performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:View all Key Company Metrics for Ionis Pharmaceuticals here>>>
Shares of Ionis Pharmaceuticals have returned -4.4% over the past month versus the Zacks S&P 500 composite's +12.2% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.