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Jazz (JAZZ) Q1 Earnings: Taking a Look at Key Metrics Versus Estimates

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For the quarter ended March 2026, Jazz Pharmaceuticals (JAZZ - Free Report) reported revenue of $1.07 billion, up 19.1% over the same period last year. EPS came in at $6.34, compared to $1.68 in the year-ago quarter.

The reported revenue represents a surprise of +9.97% over the Zacks Consensus Estimate of $972 million. With the consensus EPS estimate being $4.67, the EPS surprise was +35.91%.

While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their next move, some key metrics always offer a more accurate picture of a company's financial health.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Jazz performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
  • Total revenues- Oncology- Total: $333.4 million versus the six-analyst average estimate of $283.7 million. The reported number represents a year-over-year change of +45.3%.
  • Total revenues- Oncology- Defitelio/defibrotide: $47.4 million versus the five-analyst average estimate of $42.19 million. The reported number represents a year-over-year change of +16.6%.
  • Total revenues- Neuroscience- Oxybate- Xywav: $408.2 million versus $369.95 million estimated by five analysts on average. Compared to the year-ago quarter, this number represents a +18.4% change.
  • Total revenues- Neuroscience- Epidiolex/Epidyolex: $249.8 million compared to the $238.02 million average estimate based on five analysts. The reported number represents a change of +14.7% year over year.
  • Total revenues- Neuroscience- Oxybate (Xywav & Xyrem): $439.4 million versus the five-analyst average estimate of $390.18 million. The reported number represents a year-over-year change of +15%.
  • Total revenues- Oncology- Rylaze/Enrylaze: $103.7 million versus the five-analyst average estimate of $97.36 million. The reported number represents a year-over-year change of +10.1%.
  • Total revenues- Oncology- Vyxeos: $26.6 million versus the five-analyst average estimate of $31.62 million. The reported number represents a year-over-year change of -10%.
  • Total revenues- Oncology- Zepzelca: $101 million versus $76.2 million estimated by five analysts on average. Compared to the year-ago quarter, this number represents a +60.2% change.
  • Revenues- Product sales, net: $1.03 billion compared to the $925.25 million average estimate based on five analysts. The reported number represents a change of +22.1% year over year.
  • Total revenues - Oncology - Ziihera: $13.3 million compared to the $12.23 million average estimate based on five analysts.
  • Total revenues- Modeyso: $41.4 million compared to the $30.38 million average estimate based on five analysts.
  • Revenues- Royalties and contract revenues: $43.6 million compared to the $38.21 million average estimate based on five analysts. The reported number represents a change of -25.4% year over year.

View all Key Company Metrics for Jazz here>>>

Shares of Jazz have returned +11.4% over the past month versus the Zacks S&P 500 composite's +9.5% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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