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Compared to Estimates, Ionis Pharmaceuticals (IONS) Q2 Earnings: A Look at Key Metrics
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For the quarter ended June 2026, Ionis Pharmaceuticals (IONS - Free Report) reported revenue of $268 million, down 40.7% over the same period last year. EPS came in at -$0.43, compared to $0.86 in the year-ago quarter.
The reported revenue compares to the Zacks Consensus Estimate of $190.72 million, representing a surprise of +40.52%. The company delivered an EPS surprise of +51.69%, with the consensus EPS estimate being -$0.89.
While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.
As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.
Here is how Ionis Pharmaceuticals performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
Revenue- Total research and development revenue: $149 million versus the eight-analyst average estimate of $82.44 million. The reported number represents a year-over-year change of -57.3%.
Revenue- Total commercial revenue: $119 million versus $107.43 million estimated by eight analysts on average. Compared to the year-ago quarter, this number represents a +15.5% change.
Revenue- Royalty revenue- SPINRAZA royalties: $53 million compared to the $51.67 million average estimate based on seven analysts. The reported number represents a change of -1.9% year over year.
Revenue- Product sales, net: $31 million versus the seven-analyst average estimate of $29.23 million. The reported number represents a year-over-year change of +60.9%.
Revenue- Royalty revenue- WAINUA royalties: $16 million versus the seven-analyst average estimate of $15.23 million.
Revenue- Product sales net- DAWNZERA sales: $26 million versus the seven-analyst average estimate of $24.94 million.
Revenue- Product sales net- TRYNGOLZA sales: $5 million versus $4.28 million estimated by seven analysts on average.
Revenue- Commercial revenue- Other commercial revenue: $12 million compared to the $7.1 million average estimate based on six analysts.
Revenue- Royalty revenue: $76 million versus $71.38 million estimated by six analysts on average.
Revenue- Royalty revenue- Other royalties: $7 million compared to the $4.28 million average estimate based on six analysts.
Revenue- Research and development revenue- WAINUA joint development revenue: $16 million versus $12.86 million estimated by five analysts on average.
Revenue- Research and development revenue- Collaborative agreement revenue: $133 million versus $70.79 million estimated by five analysts on average. Compared to the year-ago quarter, this number represents a -60.5% change.
Shares of Ionis Pharmaceuticals have returned -30.3% over the past month versus the Zacks S&P 500 composite's +1.9% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.
View the Zacks #1 Rank List
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Compared to Estimates, Ionis Pharmaceuticals (IONS) Q2 Earnings: A Look at Key Metrics
For the quarter ended June 2026, Ionis Pharmaceuticals (IONS - Free Report) reported revenue of $268 million, down 40.7% over the same period last year. EPS came in at -$0.43, compared to $0.86 in the year-ago quarter.
The reported revenue compares to the Zacks Consensus Estimate of $190.72 million, representing a surprise of +40.52%. The company delivered an EPS surprise of +51.69%, with the consensus EPS estimate being -$0.89.
While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.
As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.
Here is how Ionis Pharmaceuticals performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:View all Key Company Metrics for Ionis Pharmaceuticals here>>>
Shares of Ionis Pharmaceuticals have returned -30.3% over the past month versus the Zacks S&P 500 composite's +1.9% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.