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Axsome (AXSM) Reports Q3 Earnings: What Key Metrics Have to Say

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Axsome Therapeutics (AXSM - Free Report) reported $259.69 million in revenue for the quarter ended September 2026, representing a year-over-year increase of 51.9%. EPS of -$0.25 for the same period compares to -$0.94 a year ago.

The reported revenue compares to the Zacks Consensus Estimate of $246.45 million, representing a surprise of +5.37%. The company delivered an EPS surprise of +63.77%, with the consensus EPS estimate being -$0.69.

While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Axsome performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
  • Revenues- Product sales, net: $249.95 million compared to the $245.29 million average estimate based on six analysts. The reported number represents a change of +47.2% year over year.
  • Revenues- Royalty revenue and milestone revenue: $9.74 million versus the five-analyst average estimate of $1.78 million. The reported number represents a year-over-year change of +706.3%.
  • Product Sales, net- SYMBRAVO: $3.9 million versus $5.82 million estimated by four analysts on average.
  • Product Sales, net- Auvelity: $207.6 million versus the four-analyst average estimate of $204.56 million. The reported number represents a year-over-year change of +52.5%.
  • Product Sales, net- Sunosi: $48.2 million versus $36.27 million estimated by four analysts on average. Compared to the year-ago quarter, this number represents a +47% change.

View all Key Company Metrics for Axsome here>>>

Shares of Axsome have returned -19.4% over the past month versus the Zacks S&P 500 composite's -0.9% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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