Back to top

Analyst Blog

Incyte Corporation (INCY - Analyst Report) announced full results from the phase III RECAP study on Jakafi in combination with Roche’s (RHHBY - Analyst Report) Xeloda (capecitabine). Results were presented at the annual meeting of the American Society of Clinical Oncology (ASCO).

The RECAP study evaluated Jakafi in combination with Xeloda in patients suffering from second-line metastatic pancreatic cancer. Results from the study revealed that the combination of Jakafi and Xeloda prolonged overall survival in patients with elevated C-reactive protein (CRP) compared to Xeloda alone.

Moreover, patients under the combination therapy achieved improvements in other efficacy measures like objective response rate, clinical benefit response, and weight gain. The study results also showed that the combined treatment of Jakafi and Xeloda was well tolerated.

Jakafi, Incyte’s sole marketed product, was launched in the U.S. in Nov 2011, for treating patients suffering from intermediate or high-risk myelofibrosis (MF). Jakafi contributed around $69.7 million to Incyte’s top line in the first quarter 2014, representing an increase of 44% from the year-ago quarter.

Incyte has a collaborative agreement with Novartis (NVS - Analyst Report) to market Jakafi outside the U.S. The drug has also been approved by the European Commission to treat adults suffering from primary MF, post-polycythemia vera MF or post-essential thrombocythemia MF.

Jakafi is also being studied for additional indications. Incyte, in collaboration with Novartis, is currently evaluating Jakafi in two phase III clinical trials (RESPONSE and RELIEF), for the treatment of patients suffering from polycythemia vera (PV). The company intends to submit a supplemental new drug application for Jakafi for the PV indication soon based on the positive results from the RESPONSE trial.

We are encouraged by Incyte’s progress with Jakafi. The success of Jakafi is crucial for the company. We expect investor focus to remain on Jakafi’s performance in the coming quarters.

Incyte, a biopharmaceutical company, currently carries a Zacks Rank #3 (Hold). Some better-ranked stocks in the sector include Gilead Sciences Inc. (GILD - Analyst Report). The stock holds a Zacks Rank #1 (Strong Buy).

Please login to Zacks.com or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research

Close

Are you a new Zacks Member or a visitor to Zacks.com?

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Zacks.com. Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
ERBA DIAGNO… ERB 3.00 +3.09%
SANCHEZ ENE… SN 34.18 +2.67%
THE PANTRY… PTRY 21.02 +2.09%
INTEL CP INTC 35.15 +1.88%
PIPER JAFFR… PJC 54.54 +1.70%