Back to top

Analyst Blog

Zacks Equity Research

Data Presented on BMY/PFE's Eliquis

BMY PFE

 ZacksTrade Now

This page is temporarily not available.  Please check later as it should be available shortly. If you have any questions, please email customer support at support@zacks.com or call 800-767-3771 ext.  9339.

Recently, Bristol-Myers Squibb Company (BMY - Analyst Report) and partner Pfizer Inc. (PFE - Analyst Report) announced encouraging data from a phase III study (AMPLIFY-EXT: n=2,486), which evaluated their anti-clotting drug Eliquis (apixaban) for the prevention of recurrent venous thromboembolism (VTE). The randomized, double-blind, multicenter study evaluated the drug across two doses - 2.5 mg and 5 mg versus placebo in patients, who had been previously treated for VTE. VTE includes deep vein thrombosis (DVT) and pulmonary embolism (PE).

We note that thrombosis refers to the formation of a blood clot inside a blood vessel, thereby blocking a vein (venous thrombosis) or artery (arterial thrombosis). DVT refers to a condition in which blood clots are formed in one of the large, deep veins, usually in the legs. PE is a condition, where a blood clot blocks one or more vessels in the lungs

Data from the year-long phase III study, published in the New England Journal of Medicine, revealed that treatment with Eliquis significantly reduced the recurrence of VTE and death from any cause compared to those treated with placebo. The rate of recurrence or death in the placebo arm was observed to be 11.6% as opposed to 3.8% for patients treated with Eliquis (2.5 mg) and 4.2% for those treated with 5 mg of Eliquis. Moreover, data from the study also revealed that the rate of major bleeding was comparable across all cohorts.

We remind investors that Eliquis was cleared in the EU last year for preventing VTE in adults, who have undergone elective hip or knee replacement surgery. Last month, Eliquis was approved in the EU for preventing strokes and systemic embolism in adults suffering from nonvalvular atrial fibrillation (NVAF) along with one or more risk factors for stroke. Atrial fibrillation refers to a cardiac rhythm disorder characterized by an erratic heartbeat.

We note that the US approval process of Eliquis for the NVAF indication is on track. The US Food and Drug Administration (FDA) is expected to decide on whether to approve Eliquis for the indication by March 17, 2013. Positive news from the FDA would boost the sales potential of the drug.

Neutral on Bristol-Myers/Pfizer

Currently, we have a long-term Neutral recommendation on Bristol-Myers. The stock carries a Zacks #3 Rank (Hold rating) in the short run. We have a similar stance on Pfizer.

Please login to Zacks.com or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research

Close

Are you a new Zacks Member or a visitor to Zacks.com?

Top Zacks Features

Learn more

Start for as little as $4.50 per trade.

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Zacks.com. Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
DIXIE GRP IN DXYN 15.84 +7.90%
BOFI HLDG IN BOFI 85.30 +4.97%
RAMBUS INC RMBS 12.31 +4.41%
VIPSHOP HOLD VIPS 148.73 +4.35%
NETFLIX INC NFLX 345.74 +4.32%