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Janus Henderson Global Life Sciences Fund - A Shares: (MF: JFNAX)
(NASDAQ Mutual Funds) As of Jan 14, 2026 06:22 PM ET
$80.76 USD
+0.93 (1.16%)
Zacks MF Rank
2-Buy of 5 2
Latest Performance as of Dec 31, 2025
| Total Return %* | Percentile Rank Objective | |
|---|---|---|
| YTD | 24.59 | 25 |
| 3 months | 18.59 | 15 |
| 6 months | 28.32 | 25 |
| 1 Year | 24.59 | 25 |
| 3 Year | 11.40 | 26 |
| 5 Year | 7.45 | 13 |
| 10 Year | 9.94 | 10 |
* Annual for three years and beyond.
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Portfolio Statistics
| % Unrealized Gain | 35.89 |
| % Yield | 0.31 |
| % SEC Yield | NA |
| Net Assets (Mil $) 12/31/2025 | 279.06 |
| % Turnover 12/31/2025 | 30.00 |
Risk
| 3 Year | 5 Year | 10 Year | |
|---|---|---|---|
| Beta | 0.69 | 0.63 | 0.77 |
| Alpha | -4.34 | -2.15 | -1.32 |
| R Squared | 0.30 | 0.40 | 0.53 |
| Std. Dev. | 15.08 | 15.06 | 16.14 |
| Sharpe | 0.50 | 0.35 | 2.00 |
Sector / Country Weightings
| As of 12/31/2025 | % of Portfolio |
|---|---|
| Health | 67.38 |
| Other | 9.56 |
| Finance | 9.37 |
| Services | 4.51 |
| Retail Trade | 4.18 |
| Technology | 2.68 |
| Industrial Cyclical | 2.32 |
Portfolio Holdings
| Top Equity Holdings (As of 9/30/2025) |
% of Portfolio | Value (Mil$) |
|---|---|---|
| ELI LILLY & CO | 8.31 | 379.95 |
| JOHNSON & JOHNSON | 5.01 | 229.16 |
| ASTRAZENECA PLC | 4.22 | 193.09 |
| UNITEDHEALTH GROUP INC | 4.21 | 192.29 |
| ABBVIE INC | 3.58 | 163.59 |
| ABBOTT LABORATORIES | 3.16 | 144.64 |
| ARGENX SE ADR | 2.83 | 129.15 |
| BOSTON SCIENTIFIC CORP | 2.75 | 125.49 |
| SANOFI SA | 2.69 | 122.94 |
Stock Holding % of Net Assets
| As Of | 9/30/2025 |
| Total Issues | 83 |
| Avg. P/E | 26.72 |
| Avg. P/Book | 5.88 |
| Avg. EPS Growth | 12.63 |
| Avg. Market Value (Mil $) | 188,578 |
Composition
| % of Portfolio | |
| Stocks | 99.30 |
| Foreign Stocks | 19.96 |
| Cash | 0.97 |
| Bonds | 0.00 |
| Foreign Bonds | 0.00 |
| Preferred | 0.00 |
| Convertible | 0.00 |
| Other | -0.27 |
| Foreign Hedged | 0.00 |
Style Analysis
| % of Portfolio | |
| Large Growth | NA |
| Large Value | NA |
| Small Growth | NA |
| Small Value | NA |
| Foreign Stock | NA |
| Emerging Market | NA |
| Precious Metal | NA |
| Intermediate Bond | NA |
| Foreign Bond | NA |
| High Yield Bond | NA |