Back to top

Analyst Blog

Novo Nordisk (NVO - Analyst Report) recently completed a phase IIIa study on IDegLira, which is a combination of Tresiba (insulin degludec) and Victoza (liraglutide). Novo Nordisk is evaluating IDegLira for the treatment of patients suffering from type II diabetes.

The phase III study (DUAL II) enrolled around 400 patients suffering from type II diabetes and previously insufficiently controlled on basal insulin in combination with 1–2 oral anti-diabetic agents. The study results showed that patients treated with IDegLira or Tresiba plus metformin achieved superiority compared to standalone therapy with Tresiba.

The study revealed that around 60% of the patients who used IDegLira achieved the HbA1c target of 7% (recommended by the American Diabetes Association and the European Association for the Study of Diabetes). Moreover, 45% of the patients reached the HbA1c target of 6.5% (recommended by the American Academy of Clinical Endocrinology).

Both IDegLira and Tresiba have been reported safe and tolerable. Novo Nordisk did not report any disparity between the two treatment arms as to adverse reactions and normal safety parameters.

We note that Novo Nordisk had announced results from the first phase IIIa trial of IDegLira, DUAL I, in August this year, which demonstrated an impressive efficacy profile. Novo Nordisk now plans to file regulatory applications in both the US and the EU in 2013.

Although Novo Nordisk holds a strong position in the diabetes market, we note that the diabetes market is highly crowded with players like Sanofi (SNY - Analyst Report), Eli Lilly and Company (LLY - Analyst Report) and Merck & Co. Inc. (MRK - Analyst Report).

We have an Outperform recommendation on Denmark-based Novo Nordisk. The stock carries a Zacks #2 Rank (Buy). Other large cap pharma company, that carry a Zacks #2 Rank is Johnson & Johnson (JNJ - Analyst Report).

Please login to or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research


Are you a new Zacks Member or a visitor to

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
PLANAR SYST… PLNR 4.44 +5.21%
BITAUTO HOL… BITA 81.71 +5.12%
CTPARTNERS… CTP 16.66 +4.26%
CHINA BIOLO… CBPO 47.91 +3.30%
MALLINCKROD… MNK 72.94 +2.85%