Back to top

Analyst Blog

Bristol-Myers Squibb Company (BMY - Analyst Report) and partner Pfizer Inc. (PFE - Analyst Report) recently presented encouraging data on their drug Eliquis (apixaban) from a phase III study (AMPLIFY: n=5,395). The randomized, double-blind, multicenter six-month study evaluated Eliquis as a monotherapy versus the standard of care (Sanofi’s (SNY - Analyst Report) Lovenox (enoxaparin) and warfarin) in patients suffering from acute venous thromboembolism (VTE), which includes symptomatic deep vein thrombosis (DVT) and/or pulmonary embolism (PE).

Data from the study revealed the noninferiority of Eliquis to the current standard of care in the reduction of the composite endpoint of recurrent symptomatic VTE or death related to VTE. Data from the study further revealed that major bleeding was witnessed in fewer patients in the Eliquis arm compared to those treated with the standard of care. Results from the study were published in the New England Journal of Medicine (NEJM).

Bristol-Myers/Pfizer intend to seek regulatory approvals for Eliquis for the initial and long-term treatment of VTE and for extended prevention of recurrent VTE based on data from the AMPLIFY, as well as AMPLIFY-EXT studies. We note that results from the AMPLIFY-EXT study were published in the NEJM late last year.

We note that Eliquis is already approved for reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation in multiple countries including the US. Eliquis is also approved in the EU and some other nations for prevention of VTE events in adults, who have undergone elective hip or knee replacement surgery.

While Bristol-Myers carries a Zacks Rank #4 (Sell) reflecting short-term pressure on the stock, Pfizer carries a Zacks Rank #3 (Hold). Novo Nordisk (NVO - Analyst Report) appears to be more attractive with a Zacks Rank #2 (Buy). 

Please login to Zacks.com or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research

Close

Are you a new Zacks Member or a visitor to Zacks.com?

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Zacks.com. Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
ERBA DIAGNO… ERB 3.00 +3.09%
SANCHEZ ENE… SN 34.18 +2.67%
THE PANTRY… PTRY 21.02 +2.09%
INTEL CP INTC 35.15 +1.88%
CLAYTON WIL… CWEI 117.30 +1.78%