Back to top

Analyst Blog

The US Patent and Trademark Office (USPTO) recently extended the patent covering Spectrum Pharmaceuticals’ (SPPI - Snapshot Report) Fusilev (levoleucovorin) for injection by more than two years. US patent no. 6,500,829, covering Fusilev for injection, was extended from the original date of Dec 31, 2019 to Mar 7, 2022.

Fusilev is approved in combination with chemotherapy with 5-fluorouracil as a palliative treatment for patients suffering from advanced metastatic colorectal cancer. The product is also marketed to rescue patients suffering from osteosarcoma following high-dose methotrexate therapy. Moreover, the drug is available to reduce the toxicity and combat the effects of impaired methotrexate elimination and of unintentional over dosage of folic acid antagonists.

In ex-US territories, the product is marketed by Pfizer Inc. (PFE - Analyst Report) and Sanofi (SNY - Analyst Report) among others, under various trade names.

We remind investors that Fusilev is the major contributor to Spectrum Pharma’s net product revenues. In the third quarter of 2012 Fusilev revenues came in at $52 million, representing 79% of the company’s net product sales.

We are impressed to see that Fusilev for injection patent was extended by two years. But we remain concerned about the competitive scenario in the metastatic colorectal cancer market.

We are also impressed with the company’s effort to increase the sales potential of Fusilev. In Nov 2012, the US Food & Drug Administration (FDA) approved an additional manufacturing facility to produce Fusilev for injection. Spectrum Pharma has been increasing its number of qualified third-party manufacturing sites since the approval of the product in 2011.

Spectrum Pharma carries a Zacks Rank #3 (Hold). Valeant Pharmaceuticals (VRX - Snapshot Report), carrying a Zacks Rank #1 (Strong Buy), currently appears to be more attractive in the pharma space.

Please login to Zacks.com or register to post a comment.

New to Zacks?

Start Here

Zacks Investment Research

Close

Are you a new Zacks Member or a visitor to Zacks.com?

Top Zacks Features

My Portfolio Tracker

Is it Time to Sell?

One of the most important steps you can take today is to set up your portfolio tracker on Zacks.com. Once you do, you'll be notified of major events affecting your stocks and/or funds with daily email alerts.

More Zacks Resources

Zacks Rank Home - Evaluate your stocks and use the Zacks Rank to eliminate the losers and keep the winners.

Mutual Fund Rank Home - Evaluate your funds with the Mutual Fund Rank for both your personal and retirement funds.

Stock/Mutual Fund Screening - Find better stocks and mutual funds. The ones most likely to beat the market and provide a positive return.

My Portfolio - Track your Portfolio and find out where your stocks/mutual funds stack up with the Zacks Rank.

Zacks #1 Rank Top Movers for Zacks #1 Rank Top Movers

Company Symbol Price %Chg
LITHIA MOTO… LAD 94.59 +4.60%
DELTA AIR L… DAL 39.15 +3.90%
FLAMEL TECH… FLML 14.51 +3.50%
SOUTHWEST A… LUV 28.87 +2.92%
NUSTAR GP H… NSH 41.14 +2.59%